Today I am trying to find something similar to #ifndef ONLINE_JUDGE
in python . I find a post on stackoverflow .This has worked for me . You can insert the below code in your program to do conditional compilation ....
import sys
zz=not __debug__
if not zz:
input=sys.stdin.readline
else:
sys.stdin=open('input.txt', 'r')
sys.stdout=open('output.txt','w')